Top 5 Technical Skills in Biotechnology | Best Technical Skills to Get Jobs in Biotech & Biomedical Research

Biotechnology technical skills

source – leverage edu

When a swimmer enters the water, he is expected the most to have the swimming skills, which will be considered as an unavoidable hard skill to be possessed by him. That cannot be ignored at any cost. 

Evidently hard skills are the necessity to perform any task and thus in any job application or interview, a recruiter will be searching for and expecting you to have all the essential hard skills displayed on your resume.

Biotechnology is a research-oriented field. You need to possess sound technical skills in biotechnology along with soft & transferable skills in order to get placed in a biotech or biopharmaceutical company.

If you are looking for a job, you must have hands on experience on some basic lab technique that recruiter expects you to know.

Let’s look at the Top Technical Skills in Biotechnology for getting jobs in industry and academia.

1. Polymerase chain reaction

pcr use

Source- Science learning Hub

This is one of the widely used molecular biology techniques in modern biotechnology which makes many copies of a specific DNA region, it can be thousands to million copies of it.

PCR has a wide application domain starting from DNA sequencing up to the diagnosis of infectious diseases like HIV, tuberculosis, etc.

PCR is also applied to numerous medical, diagnostic, and research procedures: genetic testing (DNA testing), genotyping, DNA sequencing, DNA cloning, genetic mapping, and forensic studies like paternity test and used for criminal recognition, etc.

There are two variants of PCR – Reverse transcription-polymerase chain reaction (RT-PCR) & quantitative (real-time) polymerase chain reaction. These PCR has its own applications which contributed in health care industry.

2.Gel electrophoresis

gel electrophoresis

source- yourgenome

Gel electrophoresis is another widely used technique in molecular biology, biochemistry, genetics, plant biotechnology, and modern biotechnology.

It is used for the separation of biological macromolecules (proteins, RNA, and DNA) by using electrophoresis method.

The different forms of Gel electrophoresis, like Native PAGE or SDS PAGE, are extensively used in industries.

It can also be utilized to investigate the results of the PCR (polymerase chain reaction).

3.Molecular (DNA) cloning

gene cloning

source – cloud clone corp

Molecular cloning or simply gene cloning is a molecular biology technique that involves the development of multiple copies of required genes by replication within host organisms.

In this technique, we clip the desired DNA segment into the bacterial gene and get millions of copies of genes of interest by replication of bacteria.

For cloning of DNA, we first treated DNA with enzymes in the test tube to generate smaller DNA fragments. After that these fragments are then combined with vector DNA to generate recombinant DNA molecules.

The recombinant DNA is then introduced into a host organism (laboratory strain of E. coli bacteria). The host organism replicates its own DNA with our recombinant DNA molecules into multiple copies. These host organisms called transgenic or genetically modified microorganisms (GMO) because contain foreign DNA fragments.

The recruiter will be looking for you to have knowledge about the basic procedures associated with this technique beginning from extraction of DNA to the use of the restriction enzymes.

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4.ELISA – Enzyme-linked immunosorbent assay


source- Bioscience notes

It is one of the majorly used “wet-lab” type analytic biochemistry assay used to measure antibodies or to detect an antigen (peptides, proteins, antibodies, and hormones), in a wet sample.

It is majorly using in pregnancy kits or even for diagnosis of HIV infection. Know more about ELISA.

If you are seeking your career in medical biotechnology, then it is the most demanding technical skill to be fetched on.

5.Tissue Culture

tissue culture

source- cloud clone corp

Tissue culture is one of the most widely used techniques in any biological or biomedical research lab. If you are a fresher looking for a placement or job, tissue culture will be a very valuable biotechnology skill to have.

Tissue culture involves the growth of cells or tissues by using growth media, such as broth or agar. Tissue culture typically refers to the growth of animal cells and tissues; whereas the term plant tissue culture is being used for the plants.

Tissue culture or cell culture is an in-vitro technique. It is an important tool for the study of the biology of cells from multicellular organisms.

Cells are grown in a culture medium that contains proper proportions of the necessary nutrients (along with proper pH) for the cells to be cultured.

There are two main types of tissue cultures: primary (mortal) cultures and cultures of established (immortal) cell lines.

Such cell lines are usually derived from tumor biopsies from cancer patients, or from primary cells that have undergone mutations, hence can propagate indefinitely.

Similar to cells in primary cultures, cells in established lines accumulate mutations over time that can change their character. Thus, in order for researchers from different laboratories to be able to compare results from experiments using the same cell lines, they must confirm the identity of the cells they are working with.

Conclusively, these are some basic and most used technique in every pharma or biomedical lab. If you are good hands-on over these techniques along with a few Modern Microbiological techniques like an inoculation, pour plate, streak plate and dilution calculations will help you step into the pharma sector, medical testing, or other microbiology labs.

If you learn instruments like HPLC and mass spectrometer, you will one step ahead in a crowd of biotechnologists.

So these technical skills could signify your practical skills while interview and make you complete with your soft skills. Now you can convince the employer, being the most appropriate candidate for any position and letting the recruiter be prideful over welcoming you to his organization.

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